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Filtered Search Results
Cercosporamide, MedChemExpress
MedChemExpress Cercosporamide is a highly potent, ATP-competitive Pkc1 kinase inhibitor, with an IC50 of Ki of Mnk inhibitor.
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Troglitazone, MedChemExpress
MedChemExpress Troglitazone is a PPARγ agonist, with EC50s of 550 nM and 780 nM for human and murine PPARγ receptor, respectively.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 441.54 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Troglitazone |
| Grade | Research |
| SMILES | O=C(SC1CC(C=C2)=CC=C2OCC3(C)OC(C(CC3)=C4C)=C(C)C(C)=C4O)NC1=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 96.46% |
| CAS | 97322-87-7 |
| Solubility Information | DMSO : 160 mg/mL (362.37 mM; Need ultrasonic) |
| Synonym | CS-045 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C24H27NO5S |
| Formula Weight | 441.54 |
3-Hydroxymandelic Acid, MedChemExpress
MedChemExpress 3-Hydroxymandelic Acid, a metabolite of Phenylephrine, Phenylephrine is a α-receptor agonist.
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SP-420, MedChemExpress
MedChemExpress SP-420 is a desferrithiocin analogue with iron-clearing efficiency with ICE value of 26.7; more potent than desferrithiocin.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 355.41 |
|---|---|
| Color | Earth Yellow |
| Physical Form | Solid |
| Chemical Name or Material | SP-420 |
| Grade | Research |
| SMILES | O=C([C@]1(C)N=C(C2=CC=C(OCCOCCOC)C=C2O)SC1)O |
| Percent Purity | 99.68% |
| CAS | 911714-45-9 |
| Solubility Information | DMSO : ≥ 38 mg/mL (106.92 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C16H21NO6S |
| Formula Weight | 355.41 |
C29, MedChemExpress
MedChemExpress C29 is a Toll-like receptor 2 (TLR2) inhibitor. C29 blocks hTLR2/1 and hTLR2/6 signaling with IC50s of 19.7 and 37.6 μM, respectively.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 285.29 |
|---|---|
| Color | Orange |
| Physical Form | Solid |
| Chemical Name or Material | C29 |
| Grade | Research |
| SMILES | OC1=C(/C=N/C2=C(C)C(C(O)=O)=CC=C2)C=CC=C1OC |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 98.0% |
| CAS | 363600-92-4 |
| Solubility Information | DMSO : ≥ 30 mg/mL (105.16 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C16H15NO4 |
| Formula Weight | 285.29 |
STF-083010, MedChemExpress
MedChemExpress STF-083010 is a specific IRE1α inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 317.38 |
|---|---|
| Color | Yellow |
| Physical Form | Powder |
| Chemical Name or Material | STF-083010 |
| Grade | Research |
| SMILES | O=S(C1=CC=CS1)(/N=C/C2=C3C=CC=CC3=CC=C2O)=O |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.0% |
| CAS | 307543-71-1 |
| Solubility Information | DMSO : 100 mg/mL (315.08 mM; Need ultrasonic) |
| Health Hazard 1 | H302 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C15H11NO3S2 |
| Formula Weight | 317.38 |
Plicamycin, MedChemExpress
MedChemExpress Plicamycin is a selective specificity protein 1 (Sp1) inhibitor. Plicamycin inhibits the growth of various cancers by decreasing Sp1 protein.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 1085.15 |
|---|---|
| Color | Yellow |
| Physical Form | Solid |
| Chemical Name or Material | Plicamycin |
| Grade | Research |
| SMILES | O=C([C@H]([C@@]([C@H](OC)C([C@@H](O)[C@H](O)C)=O)([H])C1)O[C@@](O[C@H](C)[C@H]2O)([H])C[C@H]2O[C@@](O[C@H](C)[C@@H]3O)([H])C[C@H]3O[C@@](O[C@H](C)[C@H]4O)([H])C[C@@]4(O)C)C(C1=CC5=CC(O[C@H](O[C@H](C)[C@H]6O)C[C@H]6O[C@@](O[C@H](C)[C@H]7O)([H])C[C@H]7O)=C(C)C(O)=C85)=C8O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.0% |
| CAS | 18378-89-7 |
| Solubility Information | DMSO : ≥ 100 mg/mL (92.15 mM) |
| Health Hazard 1 | H302 |
| Synonym | Mithramycin A |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C52H76O24 |
| Formula Weight | 1085.15 |
Salmeterol, MedChemExpress
MedChemExpress Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 415.57 |
|---|---|
| Color | White |
| Physical Form | Powder |
| Chemical Name or Material | Salmeterol |
| Grade | Research |
| SMILES | OC1=CC=C(C(O)CNCCCCCCOCCCCC2=CC=CC=C2)C=C1CO |
| Percent Purity | 98.72% |
| CAS | 89365-50-4 |
| Solubility Information | DMSO : ≥ 100 mg/mL (240.63 mM) |
| Synonym | GR33343X |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C25H37NO4 |
| Formula Weight | 415.57 |
Kuwanon A, MedChemExpress
MedChemExpress Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.); inhibits nitric oxide production with an IC50 of 10.5 μM.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 420.45 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | Kuwanon A |
| Grade | Research |
| SMILES | O=C1C(C/C=C(C)\C)=C(C2=C3C(C=CC(C)(C)O3)=C(O)C=C2)OC4=CC(O)=CC(O)=C14 |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 96.3% |
| CAS | 62949-77-3 |
| Purity Grade Notes | Research |
| Recommended Storage | 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
| Shelf Life | 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
| Molecular Formula | C25H24O6 |
| Formula Weight | 420.45 |
LY2510924, MedChemExpress
MedChemExpress LY2510924 is a potent and selective CXCR4 antagonist that blocks SDF-1 binding to CXCR4 with an IC50 of 0.079 nM.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 1189.45 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | LY2510924 |
| Grade | Research |
| SMILES | O=C(NCC(N[C@H](CCC(N[C@H]1CC2=CC=CC=C2)=O)C(N[C@H](C(N)=O)CCCCNC(C)C)=O)=O)[C@@H](NC([C@@](NC([C@@H](NC([C@H](NC1=O)CC3=CC=C(O)C=C3)=O)CCCCNC(C)C)=O)([H])CCCNC(N)=N)=O)CC4=CC(C=CC=C5)=C5C=C4 |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.0% |
| CAS | 1088715-84-7 |
| Solubility Information | DMSO : ≥ 125 mg/mL (105.09 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C62H88N14O10 |
| Formula Weight | 1189.45 |
Tectorigenin, MedChemExpress
MedChemExpress Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria thomsonii Benth.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 300.26 |
|---|---|
| Color | Yellow |
| Physical Form | Powder |
| Chemical Name or Material | Tectorigenin |
| Grade | Research |
| SMILES | O=C1C(C2=CC=C(O)C=C2)=COC3=CC(O)=C(OC)C(O)=C13 |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 99.04% |
| CAS | 548-77-6 |
| Solubility Information | DMSO : 120 mg/mL (399.65 mM; Need ultrasonic) |
| Health Hazard 1 | H302 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C16H12O6 |
| Formula Weight | 300.26 |
Bavachin, MedChemExpress
MedChemExpress Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 324.37 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | Bavachin |
| Grade | Research |
| SMILES | O=C1C[C@@H](C2=CC=C(O)C=C2)OC3=CC(O)=C(C/C=C(C)\C)C=C13 |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 99.74% |
| CAS | 19879-32-4 |
| Solubility Information | DMSO : 100 mg/mL (308.29 mM; Need ultrasonic) |
| Health Hazard 1 | H302+H312+H332 |
| Synonym | Corylifolin |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C20H20O4 |
| Formula Weight | 324.37 |
Capsazepine, MedChemExpress
MedChemExpress Capsazepine is a synthetic analogue of the sensory neurone excitotoxin, and an antagonist of TRPV1 receptor with an IC50 of 562 nM.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 376.9 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | Capsazepine |
| Grade | Research |
| SMILES | S=C(N1CCCC2=CC(O)=C(O)C=C2C1)NCCC3=CC=C(Cl)C=C3 |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.0% |
| CAS | 138977-28-3 |
| Solubility Information | DMSO : ≥ 100 mg/mL (265.32 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H21ClN2O2S |
| Formula Weight | 376.9 |
Rotigotine, MedChemExpress
MedChemExpress Rotigotine is a potent dopamine receptor agonist with Ki values of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors and dopamine D1 receptor. Rotigotine a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. Rotigotine can be used for parkinson's disease (PD) research.
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| Molecular Weight (g/mol) | 315.47 |
|---|---|
| Color | Off-White |
| Physical Form | Solid |
| Chemical Name or Material | Rotigotine |
| Grade | Research |
| SMILES | CCCN(CCC1=CC=CS1)[C@H]2CCC3=C(C=CC=C3O)C2 |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 95.04% |
| CAS | 99755-59-6 |
| Solubility Information | DMSO : ≥ 50 mg/mL (158.49 mM) |
| Synonym | N-0437 N-0923 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H25NOS |
| Formula Weight | 315.47 |
Macelignan, MedChemExpress
MedChemExpress Macelignan ((+)-Anwulignan; Anwuligan) is an orally active lignan isolated from Myristica fragrans. Macelignan possesses many pharmacological activities, including anti-inflammatory, anti-cancer, anti-diabetes, and neuroprotective activities.
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| Molecular Weight (g/mol) | 328.4 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Macelignan |
| Grade | Research |
| SMILES | OC1=CC=C(C[C@H](C)[C@H](C)CC2=CC=C(OCO3)C3=C2)C=C1OC |
| For Use With (Application) | Neuroscience-Neurodegeneration |
| Percent Purity | 98.0% |
| CAS | 107534-93-0 |
| Solubility Information | DMSO : 100 mg/mL (304.51 mM; Need ultrasonic) |
| Synonym | (+)-Anwulignan Anwuligan |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C20H24O4 |
| Formula Weight | 328.4 |