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H3COONNNH2H2NOCH3

CAS RN 870483-87-7

IUPAC Name: 5-({3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl}methyl)pyrimidine-2,4-diamine
Synonyms: 5-({3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl}methyl)pyrimidine-2,4-diamine
Molecular Weight (g/mol): 366.42
Molecular Formula: C20H22N4O3
InChi Key: MYQAUKPBNJWPIE-UHFFFAOYSA-N
SMILES: COC1=CC=C(COC2=C(OC)C=C(CC3=CN=C(N)N=C3N)C=C2)C=C1
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1

Tocris Bioscience™ GW 2580
GREENER_CHOICE

Selective cFMS kinase inhibitor; orally bioavailable

Target Additional RTK Inhibitors
CAS 870483-87-7
Purity >99%
Chemical Name or Material 5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
Recommended Storage Store at -20°C
Molecular Formula C20H22N4O3
Formula Weight 366.41
2

GW2580, MedChemExpress

MedChemExpress GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 μM. GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 366.41
Color Off-White
Physical Form Solid
Chemical Name or Material GW2580
Grade Research
SMILES NC1=NC(N)=C(CC2=CC(OC)=C(OCC3=CC=C(OC)C=C3)C=C2)C=N1
For Use With (Application) COVID-19-immunoregulation
Percent Purity 98.45%
CAS 870483-87-7
Solubility Information DMSO : 33.33 mg/mL (90.96 mM; Need ultrasonic) ∣Ethanol : < 1 mg/mL (insoluble)
Health Hazard 1 H302∣H315∣H319∣H335
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C20H22N4O3
Formula Weight 366.41
3

STEMCELL Technologies GW2580

CSF-1 pathway inhibitor; Inhibits cFMS

ENCOMPASS_PREFERRED
CAS 870483-87-7
Purity ≥98%
Molecular Formula C20H22N4O3
4

Tocris Bioscience™ GW 2580
GREENER_CHOICE

Selective cFMS kinase inhibitor; orally bioavailable

ENCOMPASS
5

Tocris Bioscience™ GW 2580
GREENER_CHOICE

Selective cFMS kinase inhibitor; orally bioavailable

ENCOMPASS